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Reasons for discontinuing clozapine: A cohort study of patients commencing treatment
BACKGROUND: Clozapine is uniquely effective in the management of treatment-resistant schizophrenia (TRS). However, a substantial proportion of patients discontinue treatment and this carries a poor prognosis. METHODS: We investigated the risk factors, reasons and timing of clozapine discontinuation...
Autores principales: | Legge, Sophie E., Hamshere, Marian, Hayes, Richard D., Downs, Johnny, O'Donovan, Michael C., Owen, Michael J., Walters, James T.R., MacCabe, James H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science Publisher B. V
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756540/ https://www.ncbi.nlm.nih.gov/pubmed/27211516 http://dx.doi.org/10.1016/j.schres.2016.05.002 |
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