Teaching an old pET new tricks: tuning of inclusion body formation and properties by a mixed feed system in E. coli

Against the outdated belief that inclusion bodies (IBs) in Escherichia coli are only inactive aggregates of misfolded protein, and thus should be avoided during recombinant protein production, numerous biopharmaceutically important proteins are currently produced as IBs. To obtain correctly folded,...

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Detalles Bibliográficos
Autores principales: Wurm, David J., Quehenberger, Julian, Mildner, Julia, Eggenreich, Britta, Slouka, Christoph, Schwaighofer, Andreas, Wieland, Karin, Lendl, Bernhard, Rajamanickam, Vignesh, Herwig, Christoph, Spadiut, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Biotechnological Products and Process Engineering
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756567/
https://www.ncbi.nlm.nih.gov/pubmed/29159587
http://dx.doi.org/10.1007/s00253-017-8641-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756567/
https://www.ncbi.nlm.nih.gov/pubmed/29159587
http://dx.doi.org/10.1007/s00253-017-8641-6

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