The Resistance to Plague Infection among Meriones persicus from Endemic and Non-endemic Regions in Iran: The Role of Gut Microbiota

BACKGROUND: The present study was conducted approximately 40 years ago, but its results have not been released. At the time of this study, the importance of the gut microbiota was not fully understood. METHODS: Meriones persicus rodents, as one of the major reservoirs of Yersinia pestis bacterium in...

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Autores principales: ASSMAR, Mehdi, KEYPOUR, Marjan, ROHANI, Mehdi, MOSTAFAVI, Ehsan, DANESHVAR FARHUD, Dariush
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756605/
https://www.ncbi.nlm.nih.gov/pubmed/29318122
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author ASSMAR, Mehdi
KEYPOUR, Marjan
ROHANI, Mehdi
MOSTAFAVI, Ehsan
DANESHVAR FARHUD, Dariush
author_facet ASSMAR, Mehdi
KEYPOUR, Marjan
ROHANI, Mehdi
MOSTAFAVI, Ehsan
DANESHVAR FARHUD, Dariush
author_sort ASSMAR, Mehdi
collection PubMed
description BACKGROUND: The present study was conducted approximately 40 years ago, but its results have not been released. At the time of this study, the importance of the gut microbiota was not fully understood. METHODS: Meriones persicus rodents, as one of the major reservoirs of Yersinia pestis bacterium in Iran, were compared in a disease endemic area (Akanlu, Hamadan, western Iran) and a non-endemic zone (Telo, Tehran, Iran) from 1977 to 1981. RESULTS: This study was able to transmit the resistance to Y. pestis to other rodents creatively by using and transferring gut microbiota. CONCLUSION: The study indicated for the first time that the gut microbiota could affect the sensitivity to plague in Meriones in Telo.
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spelling pubmed-57566052018-01-09 The Resistance to Plague Infection among Meriones persicus from Endemic and Non-endemic Regions in Iran: The Role of Gut Microbiota ASSMAR, Mehdi KEYPOUR, Marjan ROHANI, Mehdi MOSTAFAVI, Ehsan DANESHVAR FARHUD, Dariush Iran J Public Health Original Article BACKGROUND: The present study was conducted approximately 40 years ago, but its results have not been released. At the time of this study, the importance of the gut microbiota was not fully understood. METHODS: Meriones persicus rodents, as one of the major reservoirs of Yersinia pestis bacterium in Iran, were compared in a disease endemic area (Akanlu, Hamadan, western Iran) and a non-endemic zone (Telo, Tehran, Iran) from 1977 to 1981. RESULTS: This study was able to transmit the resistance to Y. pestis to other rodents creatively by using and transferring gut microbiota. CONCLUSION: The study indicated for the first time that the gut microbiota could affect the sensitivity to plague in Meriones in Telo. Tehran University of Medical Sciences 2018-01 /pmc/articles/PMC5756605/ /pubmed/29318122 Text en Copyright© Iranian Public Health Association & Tehran University of Medical Sciences http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
ASSMAR, Mehdi
KEYPOUR, Marjan
ROHANI, Mehdi
MOSTAFAVI, Ehsan
DANESHVAR FARHUD, Dariush
The Resistance to Plague Infection among Meriones persicus from Endemic and Non-endemic Regions in Iran: The Role of Gut Microbiota
title The Resistance to Plague Infection among Meriones persicus from Endemic and Non-endemic Regions in Iran: The Role of Gut Microbiota
title_full The Resistance to Plague Infection among Meriones persicus from Endemic and Non-endemic Regions in Iran: The Role of Gut Microbiota
title_fullStr The Resistance to Plague Infection among Meriones persicus from Endemic and Non-endemic Regions in Iran: The Role of Gut Microbiota
title_full_unstemmed The Resistance to Plague Infection among Meriones persicus from Endemic and Non-endemic Regions in Iran: The Role of Gut Microbiota
title_short The Resistance to Plague Infection among Meriones persicus from Endemic and Non-endemic Regions in Iran: The Role of Gut Microbiota
title_sort resistance to plague infection among meriones persicus from endemic and non-endemic regions in iran: the role of gut microbiota
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756605/
https://www.ncbi.nlm.nih.gov/pubmed/29318122
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