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Delayed Ejaculation: Pathophysiology, Diagnosis, and Treatment

Delayed ejaculation (DE) is a poorly defined and uncommon form of male sexual dysfunction, characterized by a marked delay in ejaculation or an inability to achieve ejaculation. It is often quite concerning to patients and their partners, and sometimes frustrates couples' attempts to conceive....

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Autores principales: Abdel-Hamid, Ibrahim A., Ali, Omar I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Sexual Medicine and Andrology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756804/
https://www.ncbi.nlm.nih.gov/pubmed/29299903
http://dx.doi.org/10.5534/wjmh.17051
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author Abdel-Hamid, Ibrahim A.
Ali, Omar I.
author_facet Abdel-Hamid, Ibrahim A.
Ali, Omar I.
author_sort Abdel-Hamid, Ibrahim A.
collection PubMed
description Delayed ejaculation (DE) is a poorly defined and uncommon form of male sexual dysfunction, characterized by a marked delay in ejaculation or an inability to achieve ejaculation. It is often quite concerning to patients and their partners, and sometimes frustrates couples' attempts to conceive. This article aims to review the pathophysiology of DE and anejaculation (AE), to explore our current understanding of the diagnosis, and to present the treatment options for this condition. Electronic databases were searched from 1966 to October 2017, including PubMed (MEDLINE) and Embase. We combined “delayed ejaculation,” “retarded ejaculation,” “inhibited ejaculation,” or “anejaculation” as Medical Subject Headings (MeSH) terms or keywords with “epidemiology,” “etiology,” “pathophysiology,” “clinical assessment,” “diagnosis,” or “treatment.” Relevant sexual medicine textbooks were searched as well. The literature suggests that the pathophysiology of DE/AE is multifactorial, including both organic and psychosocial factors. Despite the many publications on this condition, the exact pathogenesis is not yet known. There is currently no single gold standard for diagnosing DE/AE, as operationalized criteria do not exist. The history is the key to the diagnosis. Treatment should be cause-specific. There are many approaches to treatment planning, including various psychological interventions, pharmacotherapy, and specific treatments for infertile men. An approved form of drug therapy does not exist. A number of approaches can be employed for infertile men, including the collection of nocturnal emissions, prostatic massage, prostatic urethra catheterization, penile vibratory stimulation, probe electroejaculation, sperm retrieval by aspiration from either the vas deferens or the epididymis, and testicular sperm extraction.
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spelling pubmed-57568042018-01-12 Delayed Ejaculation: Pathophysiology, Diagnosis, and Treatment Abdel-Hamid, Ibrahim A. Ali, Omar I. World J Mens Health Review Article Delayed ejaculation (DE) is a poorly defined and uncommon form of male sexual dysfunction, characterized by a marked delay in ejaculation or an inability to achieve ejaculation. It is often quite concerning to patients and their partners, and sometimes frustrates couples' attempts to conceive. This article aims to review the pathophysiology of DE and anejaculation (AE), to explore our current understanding of the diagnosis, and to present the treatment options for this condition. Electronic databases were searched from 1966 to October 2017, including PubMed (MEDLINE) and Embase. We combined “delayed ejaculation,” “retarded ejaculation,” “inhibited ejaculation,” or “anejaculation” as Medical Subject Headings (MeSH) terms or keywords with “epidemiology,” “etiology,” “pathophysiology,” “clinical assessment,” “diagnosis,” or “treatment.” Relevant sexual medicine textbooks were searched as well. The literature suggests that the pathophysiology of DE/AE is multifactorial, including both organic and psychosocial factors. Despite the many publications on this condition, the exact pathogenesis is not yet known. There is currently no single gold standard for diagnosing DE/AE, as operationalized criteria do not exist. The history is the key to the diagnosis. Treatment should be cause-specific. There are many approaches to treatment planning, including various psychological interventions, pharmacotherapy, and specific treatments for infertile men. An approved form of drug therapy does not exist. A number of approaches can be employed for infertile men, including the collection of nocturnal emissions, prostatic massage, prostatic urethra catheterization, penile vibratory stimulation, probe electroejaculation, sperm retrieval by aspiration from either the vas deferens or the epididymis, and testicular sperm extraction. Korean Society for Sexual Medicine and Andrology 2018-01 2017-12-12 /pmc/articles/PMC5756804/ /pubmed/29299903 http://dx.doi.org/10.5534/wjmh.17051 Text en Copyright © 2018 Korean Society for Sexual Medicine and Andrology http://creativecommons.org/licenses/by-nc/4.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Abdel-Hamid, Ibrahim A.
Ali, Omar I.
Delayed Ejaculation: Pathophysiology, Diagnosis, and Treatment
title Delayed Ejaculation: Pathophysiology, Diagnosis, and Treatment
title_full Delayed Ejaculation: Pathophysiology, Diagnosis, and Treatment
title_fullStr Delayed Ejaculation: Pathophysiology, Diagnosis, and Treatment
title_full_unstemmed Delayed Ejaculation: Pathophysiology, Diagnosis, and Treatment
title_short Delayed Ejaculation: Pathophysiology, Diagnosis, and Treatment
title_sort delayed ejaculation: pathophysiology, diagnosis, and treatment
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756804/
https://www.ncbi.nlm.nih.gov/pubmed/29299903
http://dx.doi.org/10.5534/wjmh.17051
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