Development of In Vitro Drug-Induced Cardiotoxicity Assay by Using Three-Dimensional Cardiac Tissues Derived from Human Induced Pluripotent Stem Cells

An in vitro drug-induced cardiotoxicity assay is a critical step in drug discovery for clinical use. The use of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) is promising for this purpose. However, single hiPSC-CMs are limited in their ability to mimic native cardiac tissue...

Descripción completa

Detalles Bibliográficos
Autores principales: Takeda, Maki, Miyagawa, Shigeru, Fukushima, Satsuki, Saito, Atsuhiro, Ito, Emiko, Harada, Akima, Matsuura, Ryohei, Iseoka, Hiroko, Sougawa, Nagako, Mochizuki-Oda, Noriko, Matsusaki, Michiya, Akashi, Mitsuru, Sawa, Yoshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757089/
https://www.ncbi.nlm.nih.gov/pubmed/28967302
http://dx.doi.org/10.1089/ten.tec.2017.0247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757089/
https://www.ncbi.nlm.nih.gov/pubmed/28967302
http://dx.doi.org/10.1089/ten.tec.2017.0247

Ejemplares similares