Cancer chemoprevention and therapy using chinese herbal medicine

Traditional Chinese medicine (TCM) plays an indispensable role in cancer prevention and treatment. Chinese herbal medicine (CHM) is a key component of TCM and has been practiced for thousands of years. A number of naturally occurring products from Chinese herbs extracts exhibit strong inhibitory pro...

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Detalles Bibliográficos
Autores principales: Jiao, Lijing, Bi, Ling, Lu, Yan, Wang, Qin, Gong, Yabin, Shi, Jun, Xu, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757296/
https://www.ncbi.nlm.nih.gov/pubmed/29321719
http://dx.doi.org/10.1186/s12575-017-0066-1
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author Jiao, Lijing
Bi, Ling
Lu, Yan
Wang, Qin
Gong, Yabin
Shi, Jun
Xu, Ling
author_facet Jiao, Lijing
Bi, Ling
Lu, Yan
Wang, Qin
Gong, Yabin
Shi, Jun
Xu, Ling
author_sort Jiao, Lijing
collection PubMed
description Traditional Chinese medicine (TCM) plays an indispensable role in cancer prevention and treatment. Chinese herbal medicine (CHM) is a key component of TCM and has been practiced for thousands of years. A number of naturally occurring products from Chinese herbs extracts exhibit strong inhibitory properties against carcinogenesis, including CHM single-herb extracts, CHM-derived active components, and CHM formulas (the polyherbal combinations), which regulate JAK/STAT, MAPK, and NF-ҡB pathways. The present review aims to report the cancer-preventive effect of CHM with evidence from cell-line, animal, epidemiological, and clinical experiments. We also present several issues that have yet to be resolved. In the future, cancer prevention by CHM will face unprecedented opportunities and challenges.
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spelling pubmed-57572962018-01-10 Cancer chemoprevention and therapy using chinese herbal medicine Jiao, Lijing Bi, Ling Lu, Yan Wang, Qin Gong, Yabin Shi, Jun Xu, Ling Biol Proced Online Review Traditional Chinese medicine (TCM) plays an indispensable role in cancer prevention and treatment. Chinese herbal medicine (CHM) is a key component of TCM and has been practiced for thousands of years. A number of naturally occurring products from Chinese herbs extracts exhibit strong inhibitory properties against carcinogenesis, including CHM single-herb extracts, CHM-derived active components, and CHM formulas (the polyherbal combinations), which regulate JAK/STAT, MAPK, and NF-ҡB pathways. The present review aims to report the cancer-preventive effect of CHM with evidence from cell-line, animal, epidemiological, and clinical experiments. We also present several issues that have yet to be resolved. In the future, cancer prevention by CHM will face unprecedented opportunities and challenges. BioMed Central 2018-01-08 /pmc/articles/PMC5757296/ /pubmed/29321719 http://dx.doi.org/10.1186/s12575-017-0066-1 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Jiao, Lijing
Bi, Ling
Lu, Yan
Wang, Qin
Gong, Yabin
Shi, Jun
Xu, Ling
Cancer chemoprevention and therapy using chinese herbal medicine
title Cancer chemoprevention and therapy using chinese herbal medicine
title_full Cancer chemoprevention and therapy using chinese herbal medicine
title_fullStr Cancer chemoprevention and therapy using chinese herbal medicine
title_full_unstemmed Cancer chemoprevention and therapy using chinese herbal medicine
title_short Cancer chemoprevention and therapy using chinese herbal medicine
title_sort cancer chemoprevention and therapy using chinese herbal medicine
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757296/
https://www.ncbi.nlm.nih.gov/pubmed/29321719
http://dx.doi.org/10.1186/s12575-017-0066-1
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