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Floaters and reduced contrast sensitivity after successful pharmacologic vitreolysis with ocriplasmin

PURPOSE: To describe the onset of floaters and reduction in contrast sensitivity (CS) following successful pharmacologic vitreolysis with ocriplasmin for the treatment of vitreo-macular traction (VMT) in a patient with previously normal CS. OBSERVATIONS: A 65-year-old woman with a past ocular histor...

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Detalles Bibliográficos
Autores principales: Khoshnevis, Matin, Nguyen-Cuu, Jeannie, Sebag, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757454/
https://www.ncbi.nlm.nih.gov/pubmed/29503926
http://dx.doi.org/10.1016/j.ajoc.2016.08.005
Descripción
Sumario:PURPOSE: To describe the onset of floaters and reduction in contrast sensitivity (CS) following successful pharmacologic vitreolysis with ocriplasmin for the treatment of vitreo-macular traction (VMT) in a patient with previously normal CS. OBSERVATIONS: A 65-year-old woman with a past ocular history of normal visual acuity (VA = 20/26) and contrast sensitivity (1.81% Weber) presents with a 4-month history of distortions. VA decreased to 20/40 and Optical Coherence Tomography (OCT) demonstrated VMT. Pharmacologic vitreolysis was performed with intravitreal ocriplasmin. Ten weeks later the patient complained of floaters and was found to have a PVD and complete resolution of VMT. VA was still 20/40, but contrast sensitivity decreased by more than 100% to 3.77%Weber. After 6 months of attempted coping, this did not improve, so limited vitrectomy was performed. Post-operative VA = 20/26 and CS improved by 46% from 3.77%W to 2.03%W (normal). CONCLUSION: and importance: This case highlights a little discussed consequence of PVD induction by successful pharmacologic vitreolysis – the development of clinically significant floaters. The resulting reduction of contrast sensitivity was normalized by limited vitrectomy, strongly suggesting that the detached vitreous was the cause.