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Floaters and reduced contrast sensitivity after successful pharmacologic vitreolysis with ocriplasmin
PURPOSE: To describe the onset of floaters and reduction in contrast sensitivity (CS) following successful pharmacologic vitreolysis with ocriplasmin for the treatment of vitreo-macular traction (VMT) in a patient with previously normal CS. OBSERVATIONS: A 65-year-old woman with a past ocular histor...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757454/ https://www.ncbi.nlm.nih.gov/pubmed/29503926 http://dx.doi.org/10.1016/j.ajoc.2016.08.005 |
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author | Khoshnevis, Matin Nguyen-Cuu, Jeannie Sebag, J. |
author_facet | Khoshnevis, Matin Nguyen-Cuu, Jeannie Sebag, J. |
author_sort | Khoshnevis, Matin |
collection | PubMed |
description | PURPOSE: To describe the onset of floaters and reduction in contrast sensitivity (CS) following successful pharmacologic vitreolysis with ocriplasmin for the treatment of vitreo-macular traction (VMT) in a patient with previously normal CS. OBSERVATIONS: A 65-year-old woman with a past ocular history of normal visual acuity (VA = 20/26) and contrast sensitivity (1.81% Weber) presents with a 4-month history of distortions. VA decreased to 20/40 and Optical Coherence Tomography (OCT) demonstrated VMT. Pharmacologic vitreolysis was performed with intravitreal ocriplasmin. Ten weeks later the patient complained of floaters and was found to have a PVD and complete resolution of VMT. VA was still 20/40, but contrast sensitivity decreased by more than 100% to 3.77%Weber. After 6 months of attempted coping, this did not improve, so limited vitrectomy was performed. Post-operative VA = 20/26 and CS improved by 46% from 3.77%W to 2.03%W (normal). CONCLUSION: and importance: This case highlights a little discussed consequence of PVD induction by successful pharmacologic vitreolysis – the development of clinically significant floaters. The resulting reduction of contrast sensitivity was normalized by limited vitrectomy, strongly suggesting that the detached vitreous was the cause. |
format | Online Article Text |
id | pubmed-5757454 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-57574542018-03-02 Floaters and reduced contrast sensitivity after successful pharmacologic vitreolysis with ocriplasmin Khoshnevis, Matin Nguyen-Cuu, Jeannie Sebag, J. Am J Ophthalmol Case Rep Case report PURPOSE: To describe the onset of floaters and reduction in contrast sensitivity (CS) following successful pharmacologic vitreolysis with ocriplasmin for the treatment of vitreo-macular traction (VMT) in a patient with previously normal CS. OBSERVATIONS: A 65-year-old woman with a past ocular history of normal visual acuity (VA = 20/26) and contrast sensitivity (1.81% Weber) presents with a 4-month history of distortions. VA decreased to 20/40 and Optical Coherence Tomography (OCT) demonstrated VMT. Pharmacologic vitreolysis was performed with intravitreal ocriplasmin. Ten weeks later the patient complained of floaters and was found to have a PVD and complete resolution of VMT. VA was still 20/40, but contrast sensitivity decreased by more than 100% to 3.77%Weber. After 6 months of attempted coping, this did not improve, so limited vitrectomy was performed. Post-operative VA = 20/26 and CS improved by 46% from 3.77%W to 2.03%W (normal). CONCLUSION: and importance: This case highlights a little discussed consequence of PVD induction by successful pharmacologic vitreolysis – the development of clinically significant floaters. The resulting reduction of contrast sensitivity was normalized by limited vitrectomy, strongly suggesting that the detached vitreous was the cause. Elsevier 2016-08-28 /pmc/articles/PMC5757454/ /pubmed/29503926 http://dx.doi.org/10.1016/j.ajoc.2016.08.005 Text en © 2016 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Case report Khoshnevis, Matin Nguyen-Cuu, Jeannie Sebag, J. Floaters and reduced contrast sensitivity after successful pharmacologic vitreolysis with ocriplasmin |
title | Floaters and reduced contrast sensitivity after successful pharmacologic vitreolysis with ocriplasmin |
title_full | Floaters and reduced contrast sensitivity after successful pharmacologic vitreolysis with ocriplasmin |
title_fullStr | Floaters and reduced contrast sensitivity after successful pharmacologic vitreolysis with ocriplasmin |
title_full_unstemmed | Floaters and reduced contrast sensitivity after successful pharmacologic vitreolysis with ocriplasmin |
title_short | Floaters and reduced contrast sensitivity after successful pharmacologic vitreolysis with ocriplasmin |
title_sort | floaters and reduced contrast sensitivity after successful pharmacologic vitreolysis with ocriplasmin |
topic | Case report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757454/ https://www.ncbi.nlm.nih.gov/pubmed/29503926 http://dx.doi.org/10.1016/j.ajoc.2016.08.005 |
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