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Ozurdex completely located inside a crystallized lens - Results of 14 months

PURPOSE: To report the therapeutic efficacy and results of an accidentally injected intralenticular sustained-release dexamethasone implant (Ozurdex) in a patient with macular edema secondary to central retinal vein occlusion at 14 months after injection. OBSERVATIONS: We present a 70-year-old femal...

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Autores principales: Baskan, Burhan, Cıcek, Ayşe, Gulhan, Ahmet, Gundogan, Medine, Goktas, Sertan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757461/
https://www.ncbi.nlm.nih.gov/pubmed/29503921
http://dx.doi.org/10.1016/j.ajoc.2016.08.001
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author Baskan, Burhan
Cıcek, Ayşe
Gulhan, Ahmet
Gundogan, Medine
Goktas, Sertan
author_facet Baskan, Burhan
Cıcek, Ayşe
Gulhan, Ahmet
Gundogan, Medine
Goktas, Sertan
author_sort Baskan, Burhan
collection PubMed
description PURPOSE: To report the therapeutic efficacy and results of an accidentally injected intralenticular sustained-release dexamethasone implant (Ozurdex) in a patient with macular edema secondary to central retinal vein occlusion at 14 months after injection. OBSERVATIONS: We present a 70-year-old female patient with central retinal vein occlusion who underwent an Ozurdex injection. Patient discontinued from the treatment period during the 14-month and there was no ophthalmologic examination of the patient. Detailed ophthalmological examination was performed. Ozurdex localization was determined by Pentacam rotating Scheimpflug System. The implant was accidentally injected into the crystalline lens. It did not cause a totally lens opacification but did result only in a posterior subcapsular cataract. The macular edema did not resolve, and the patient underwent phacoemulsification surgery. CONCLUSIONS AND IMPORTANCE: Ozurdex that totally located inside the crystallize lens may not have the therapeutic effects.
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spelling pubmed-57574612018-03-02 Ozurdex completely located inside a crystallized lens - Results of 14 months Baskan, Burhan Cıcek, Ayşe Gulhan, Ahmet Gundogan, Medine Goktas, Sertan Am J Ophthalmol Case Rep Case report PURPOSE: To report the therapeutic efficacy and results of an accidentally injected intralenticular sustained-release dexamethasone implant (Ozurdex) in a patient with macular edema secondary to central retinal vein occlusion at 14 months after injection. OBSERVATIONS: We present a 70-year-old female patient with central retinal vein occlusion who underwent an Ozurdex injection. Patient discontinued from the treatment period during the 14-month and there was no ophthalmologic examination of the patient. Detailed ophthalmological examination was performed. Ozurdex localization was determined by Pentacam rotating Scheimpflug System. The implant was accidentally injected into the crystalline lens. It did not cause a totally lens opacification but did result only in a posterior subcapsular cataract. The macular edema did not resolve, and the patient underwent phacoemulsification surgery. CONCLUSIONS AND IMPORTANCE: Ozurdex that totally located inside the crystallize lens may not have the therapeutic effects. Elsevier 2016-08-11 /pmc/articles/PMC5757461/ /pubmed/29503921 http://dx.doi.org/10.1016/j.ajoc.2016.08.001 Text en © 2016 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case report
Baskan, Burhan
Cıcek, Ayşe
Gulhan, Ahmet
Gundogan, Medine
Goktas, Sertan
Ozurdex completely located inside a crystallized lens - Results of 14 months
title Ozurdex completely located inside a crystallized lens - Results of 14 months
title_full Ozurdex completely located inside a crystallized lens - Results of 14 months
title_fullStr Ozurdex completely located inside a crystallized lens - Results of 14 months
title_full_unstemmed Ozurdex completely located inside a crystallized lens - Results of 14 months
title_short Ozurdex completely located inside a crystallized lens - Results of 14 months
title_sort ozurdex completely located inside a crystallized lens - results of 14 months
topic Case report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757461/
https://www.ncbi.nlm.nih.gov/pubmed/29503921
http://dx.doi.org/10.1016/j.ajoc.2016.08.001
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