Bortezomib inhibits proliferation, migration, and TGF-β1–induced epithelial–mesenchymal transition of RPE cells

PURPOSE: Nuclear factor kappa B (NF-κB) plays an important role in the epithelial–mesenchymal transition (EMT) of RPE cells. We investigated the effects of a proteasome inhibitor, bortezomib, on the EMT in RPE cells. In addition, we assessed the influence of bortezomib on regulation of the NF-κB pat...

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Detalles Bibliográficos
Autores principales: Moon, Kun, Lee, Hyun-Gyo, Baek, Won-Ki, Lee, Youngkyun, Kim, Kwang Soo, Jun, Jong Hwa, Kim, Jae-Young, Joo, Choun-Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757857/
https://www.ncbi.nlm.nih.gov/pubmed/29386876

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