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Profiles of pro-opiomelanocortin and encoded peptides, and their processing enzymes in equine pituitary pars intermedia dysfunction

Equine pituitary pars intermedia dysfunction (PPID) is characterized by hyperplasia of the pars intermedia (PI) melanotrophs of the pituitary gland (PG), and increased production of proopiomelanocortin (POMC). POMC is cleaved by prohormone convertase 1 (PC1) to produce adrenocorticotropic hormone (A...

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Detalles Bibliográficos
Autores principales: Carmalt, James L., Mortazavi, Sima, McOnie, Rebecca C., Allen, Andrew L., Unniappan, Suraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757946/
https://www.ncbi.nlm.nih.gov/pubmed/29309431
http://dx.doi.org/10.1371/journal.pone.0190796