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Juvenile X-linked retinoschisis responsive to intravitreal corticosteroids

PURPOSE: To report the case of an adult male with X-linked retinoschisis (XLRS) who presented with cystoid macular edema (CME) that responded consistently to treatment with intravitreal steroids. OBSERVATIONS: A 39 year old male with unilateral presentation of CME after repair of a retinal detachmen...

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Detalles Bibliográficos
Autores principales: Ansari, Waseem H., Browne, Andrew W., Singh, Rishi P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758014/
https://www.ncbi.nlm.nih.gov/pubmed/29503947
http://dx.doi.org/10.1016/j.ajoc.2016.12.002
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author Ansari, Waseem H.
Browne, Andrew W.
Singh, Rishi P.
author_facet Ansari, Waseem H.
Browne, Andrew W.
Singh, Rishi P.
author_sort Ansari, Waseem H.
collection PubMed
description PURPOSE: To report the case of an adult male with X-linked retinoschisis (XLRS) who presented with cystoid macular edema (CME) that responded consistently to treatment with intravitreal steroids. OBSERVATIONS: A 39 year old male with unilateral presentation of CME after repair of a retinal detachment secondary to XLRS responded initially to an injection of intravitreal triamcinolone acetonide (IVTA). Central subfield thickness on OCT was reduced. Three months later, the CME recurred and he was unresponsive to topical treatment so repeat IVTA was given, and the CME once again was reduced dramatically. After the next recurrence, intravitreal dexamethasone implant treatment was initiated and successful at treating recurrences in 3 month intervals for 5 additional injections. Finally, an intravitreal fluocinolone acetonide implant was surgically placed with control of CME. CONCLUSIONS AND IMPORTANCE: Corticosteroids have never been reported to be effective in CME related to XLRS. Here, we document a case of a man who successfully had decrease of intraretinal fluid and schisis with treatment of intravitreal corticosteroids as demonstrated by spectral domain optical coherence tomography.
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spelling pubmed-57580142018-03-02 Juvenile X-linked retinoschisis responsive to intravitreal corticosteroids Ansari, Waseem H. Browne, Andrew W. Singh, Rishi P. Am J Ophthalmol Case Rep Case report PURPOSE: To report the case of an adult male with X-linked retinoschisis (XLRS) who presented with cystoid macular edema (CME) that responded consistently to treatment with intravitreal steroids. OBSERVATIONS: A 39 year old male with unilateral presentation of CME after repair of a retinal detachment secondary to XLRS responded initially to an injection of intravitreal triamcinolone acetonide (IVTA). Central subfield thickness on OCT was reduced. Three months later, the CME recurred and he was unresponsive to topical treatment so repeat IVTA was given, and the CME once again was reduced dramatically. After the next recurrence, intravitreal dexamethasone implant treatment was initiated and successful at treating recurrences in 3 month intervals for 5 additional injections. Finally, an intravitreal fluocinolone acetonide implant was surgically placed with control of CME. CONCLUSIONS AND IMPORTANCE: Corticosteroids have never been reported to be effective in CME related to XLRS. Here, we document a case of a man who successfully had decrease of intraretinal fluid and schisis with treatment of intravitreal corticosteroids as demonstrated by spectral domain optical coherence tomography. Elsevier 2016-12-03 /pmc/articles/PMC5758014/ /pubmed/29503947 http://dx.doi.org/10.1016/j.ajoc.2016.12.002 Text en © 2016 Published by Elsevier Inc. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case report
Ansari, Waseem H.
Browne, Andrew W.
Singh, Rishi P.
Juvenile X-linked retinoschisis responsive to intravitreal corticosteroids
title Juvenile X-linked retinoschisis responsive to intravitreal corticosteroids
title_full Juvenile X-linked retinoschisis responsive to intravitreal corticosteroids
title_fullStr Juvenile X-linked retinoschisis responsive to intravitreal corticosteroids
title_full_unstemmed Juvenile X-linked retinoschisis responsive to intravitreal corticosteroids
title_short Juvenile X-linked retinoschisis responsive to intravitreal corticosteroids
title_sort juvenile x-linked retinoschisis responsive to intravitreal corticosteroids
topic Case report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758014/
https://www.ncbi.nlm.nih.gov/pubmed/29503947
http://dx.doi.org/10.1016/j.ajoc.2016.12.002
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