IntOGen-mutations identifies cancer drivers across tumor types

The IntOGen-mutations platform (http://www.intogen.org/mutations/) summarizes somatic mutations, genes and pathways involved in tumorigenesis. It identifies and visualizes cancer drivers, analyzing 4,623 exomes from 13 cancer sites. It provides support to cancer researchers, aids the identification...

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Detalles Bibliográficos
Autores principales: Gonzalez-Perez, Abel, Perez-Llamas, Christian, Deu-Pons, Jordi, Tamborero, David, Schroeder, Michael P, Jene-Sanz, Alba, Santos, Alberto, Lopez-Bigas, Nuria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758042/
https://www.ncbi.nlm.nih.gov/pubmed/24037244
http://dx.doi.org/10.1038/nmeth.2642
Descripción
Sumario:The IntOGen-mutations platform (http://www.intogen.org/mutations/) summarizes somatic mutations, genes and pathways involved in tumorigenesis. It identifies and visualizes cancer drivers, analyzing 4,623 exomes from 13 cancer sites. It provides support to cancer researchers, aids the identification of drivers across tumor cohorts and helps rank mutations for better clinical decision-making. SUPPLEMENTARY INFORMATION: The online version of this article (doi:10.1038/nmeth.2642) contains supplementary material, which is available to authorized users.

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