IntOGen-mutations identifies cancer drivers across tumor types

The IntOGen-mutations platform (http://www.intogen.org/mutations/) summarizes somatic mutations, genes and pathways involved in tumorigenesis. It identifies and visualizes cancer drivers, analyzing 4,623 exomes from 13 cancer sites. It provides support to cancer researchers, aids the identification...

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Autores principales: Gonzalez-Perez, Abel, Perez-Llamas, Christian, Deu-Pons, Jordi, Tamborero, David, Schroeder, Michael P, Jene-Sanz, Alba, Santos, Alberto, Lopez-Bigas, Nuria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758042/
https://www.ncbi.nlm.nih.gov/pubmed/24037244
http://dx.doi.org/10.1038/nmeth.2642
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author Gonzalez-Perez, Abel
Perez-Llamas, Christian
Deu-Pons, Jordi
Tamborero, David
Schroeder, Michael P
Jene-Sanz, Alba
Santos, Alberto
Lopez-Bigas, Nuria
author_facet Gonzalez-Perez, Abel
Perez-Llamas, Christian
Deu-Pons, Jordi
Tamborero, David
Schroeder, Michael P
Jene-Sanz, Alba
Santos, Alberto
Lopez-Bigas, Nuria
author_sort Gonzalez-Perez, Abel
collection PubMed
description The IntOGen-mutations platform (http://www.intogen.org/mutations/) summarizes somatic mutations, genes and pathways involved in tumorigenesis. It identifies and visualizes cancer drivers, analyzing 4,623 exomes from 13 cancer sites. It provides support to cancer researchers, aids the identification of drivers across tumor cohorts and helps rank mutations for better clinical decision-making. SUPPLEMENTARY INFORMATION: The online version of this article (doi:10.1038/nmeth.2642) contains supplementary material, which is available to authorized users.
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spelling pubmed-57580422018-01-08 IntOGen-mutations identifies cancer drivers across tumor types Gonzalez-Perez, Abel Perez-Llamas, Christian Deu-Pons, Jordi Tamborero, David Schroeder, Michael P Jene-Sanz, Alba Santos, Alberto Lopez-Bigas, Nuria Nat Methods Article The IntOGen-mutations platform (http://www.intogen.org/mutations/) summarizes somatic mutations, genes and pathways involved in tumorigenesis. It identifies and visualizes cancer drivers, analyzing 4,623 exomes from 13 cancer sites. It provides support to cancer researchers, aids the identification of drivers across tumor cohorts and helps rank mutations for better clinical decision-making. SUPPLEMENTARY INFORMATION: The online version of this article (doi:10.1038/nmeth.2642) contains supplementary material, which is available to authorized users. Nature Publishing Group US 2013-09-15 2013 /pmc/articles/PMC5758042/ /pubmed/24037244 http://dx.doi.org/10.1038/nmeth.2642 Text en © The Author(s) 2013 This work is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/.
spellingShingle Article
Gonzalez-Perez, Abel
Perez-Llamas, Christian
Deu-Pons, Jordi
Tamborero, David
Schroeder, Michael P
Jene-Sanz, Alba
Santos, Alberto
Lopez-Bigas, Nuria
IntOGen-mutations identifies cancer drivers across tumor types
title IntOGen-mutations identifies cancer drivers across tumor types
title_full IntOGen-mutations identifies cancer drivers across tumor types
title_fullStr IntOGen-mutations identifies cancer drivers across tumor types
title_full_unstemmed IntOGen-mutations identifies cancer drivers across tumor types
title_short IntOGen-mutations identifies cancer drivers across tumor types
title_sort intogen-mutations identifies cancer drivers across tumor types
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758042/
https://www.ncbi.nlm.nih.gov/pubmed/24037244
http://dx.doi.org/10.1038/nmeth.2642
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