Cargando…

IntOGen-mutations identifies cancer drivers across tumor types

The IntOGen-mutations platform (http://www.intogen.org/mutations/) summarizes somatic mutations, genes and pathways involved in tumorigenesis. It identifies and visualizes cancer drivers, analyzing 4,623 exomes from 13 cancer sites. It provides support to cancer researchers, aids the identification...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gonzalez-Perez, Abel, Perez-Llamas, Christian, Deu-Pons, Jordi, Tamborero, David, Schroeder, Michael P, Jene-Sanz, Alba, Santos, Alberto, Lopez-Bigas, Nuria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group US 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758042/ https://www.ncbi.nlm.nih.gov/pubmed/24037244 http://dx.doi.org/10.1038/nmeth.2642

Ejemplares similares

Integrative Cancer Genomics (IntOGen) in Biomart
por: Perez-Llamas, Christian, et al.
Publicado: (2011)

Comprehensive identification of mutational cancer driver genes across 12 tumor types
por: Tamborero, David, et al.
Publicado: (2013)

Rational design of cancer gene panels with OncoPaD
por: Rubio-Perez, Carlota, et al.
Publicado: (2016)

OncodriveFML: a general framework to identify coding and non-coding regions with cancer driver mutations
por: Mularoni, Loris, et al.
Publicado: (2016)

The mutational landscape of chromatin regulatory factors across 4,623 tumor samples
por: Gonzalez-Perez, Abel, et al.
Publicado: (2013)

Improving the prediction of the functional impact of cancer mutations by baseline tolerance transformation
por: Gonzalez-Perez, Abel, et al.
Publicado: (2012)

OncodriveROLE classifies cancer driver genes in loss of function and activating mode of action
por: Schroeder, Michael P., et al.
Publicado: (2014)

Oncodrive-CIS: A Method to Reveal Likely Driver Genes Based on the Impact of Their Copy Number Changes on Expression
por: Tamborero, David, et al.
Publicado: (2013)

Cancer Genome Interpreter annotates the biological and clinical relevance of tumor alterations
por: Tamborero, David, et al.
Publicado: (2018)

Functional impact bias reveals cancer drivers
por: Gonzalez-Perez, Abel, et al.
Publicado: (2012)

Discovering the drivers of clonal hematopoiesis
por: Pich, Oriol, et al.
Publicado: (2022)

OncodriveCLUSTL: a sequence-based clustering method to identify cancer drivers
por: Arnedo-Pac, Claudia, et al.
Publicado: (2019)

OncodriveCLUSTL: a sequence-based clustering method to identify cancer drivers
por: Arnedo-Pac, Claudia, et al.
Publicado: (2019)

Altered oncomodules underlie chromatin regulatory factors driver mutations
por: Frigola, Joan, et al.
Publicado: (2016)

Gitools: Analysis and Visualisation of Genomic Data Using Interactive Heat-Maps
por: Perez-Llamas, Christian, et al.
Publicado: (2011)

Visualizing multidimensional cancer genomics data
por: Schroeder, Michael P, et al.
Publicado: (2013)

Urinary Plasmin(ogen): New Predictor of Hypertension?
por: Kohan, Donald E.
Publicado: (2018)

P1337: IDENTIFICATION OF CLONAL HEMATOPOIESIS DRIVER MUTATIONS THROUGH IN SILICO SATURATION MUTAGENESIS
por: Demajo, Santiago, et al.
Publicado: (2023)

Fibrin(ogen) mediates acute inflammatory responses to biomaterials
Publicado: (1993)

Urinary Plasmin(ogen) as a Prognostic Factor for Hypertension
por: Ray, Evan C., et al.
Publicado: (2018)

Fibrin(ogen) in human disease: both friend and foe
por: Vilar, Rui, et al.
Publicado: (2020)

Fibrin(ogen) as a Therapeutic Target: Opportunities and Challenges
por: Gaule, Thembaninkosi G., et al.
Publicado: (2021)

Thrombin–Fibrin(ogen) Interactions, Host Defense and Risk of Thrombosis
por: Hulshof, Anne-Marije, et al.
Publicado: (2021)

Cellular mechanisms of fibrin (ogen): insight from neurodegenerative diseases
por: Wen, Tingting, et al.
Publicado: (2023)

Beneficial and Detrimental Effects of Plasmin(ogen) during Infection and Sepsis in Mice
por: Guo, Yongzhi, et al.
Publicado: (2011)

Circuits of cancer drivers revealed by convergent misregulation of transcription factor targets across tumor types
por: Gonzalez-Perez, Abel
Publicado: (2016)

Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study
por: Panoutsopoulou, K, et al.
Publicado: (2010)

Pan-Cancer Network Analysis Identifies Combinations of Rare Somatic Mutations across Pathways and Protein Complexes
por: Leiserson, Mark D.M., et al.
Publicado: (2014)

DisGeNET: a comprehensive platform integrating information on human disease-associated genes and variants
por: Piñero, Janet, et al.
Publicado: (2017)

Copy number footprints of platinum-based anticancer therapies
por: Gonzalez, Santiago, et al.
Publicado: (2023)

Spatial Distribution of Factor Xa, Thrombin, and Fibrin(ogen) on Thrombi at Venous Shear
por: Berny, Michelle A., et al.
Publicado: (2010)

The role of fibrinogen, fibrin and fibrin(ogen) degradation products (FDPs) in tumor progression
por: Kołodziejczyk, Joanna, et al.
Publicado: (2013)

Serum amyloid A binds to fibrin(ogen), promoting fibrin amyloid formation
por: Page, Martin J., et al.
Publicado: (2019)

Physical Activity, Weight Loss, and Weight Maintenance in the DiOGenes Multicenter Trial
por: van Baak, Marleen A., et al.
Publicado: (2021)

Inhibition of Specific NF-κB Activity Contributes to the Tumor Suppressor Function of 14-3-3σ in Breast Cancer
por: Inglés-Esteve, Julia, et al.
Publicado: (2012)

Genetic Polymorphisms in the Hypothalamic Pathway in Relation to Subsequent Weight Change – The DiOGenes Study
por: Du, Huaidong, et al.
Publicado: (2011)

In vitro characterization of jellyfish venom fibrin(ogen)olytic enzymes from Nemopilema nomurai
por: Bae, Seong Kyeong, et al.
Publicado: (2017)

Expression and ultrastructural localization of plasmin(ogen) in the terminally differentiated layers of normal human epidermis
por: Voegeli, R., et al.
Publicado: (2019)

Fibrin(ogen) Is Constitutively Expressed by Differentiated Intestinal Epithelial Cells and Mediates Wound Healing
por: Seltana, Amira, et al.
Publicado: (2022)

Plasmapheresis to remove amyloid fibrin(ogen) particles for treating the post‐COVID‐19 condition
por: Fox, Tilly, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_qm998vtief5j7u5jicqqshju1f