Combined (1)H-Detected Solid-State NMR Spectroscopy and Electron Cryotomography to Study Membrane Proteins across Resolutions in Native Environments

Membrane proteins remain challenging targets for structural biology, despite much effort, as their native environment is heterogeneous and complex. Most methods rely on detergents to extract membrane proteins from their native environment, but this removal can significantly alter the structure and f...

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Detalles Bibliográficos
Autores principales: Baker, Lindsay A., Sinnige, Tessa, Schellenberger, Pascale, de Keyzer, Jeanine, Siebert, C. Alistair, Driessen, Arnold J.M., Baldus, Marc, Grünewald, Kay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758107/
https://www.ncbi.nlm.nih.gov/pubmed/29249608
http://dx.doi.org/10.1016/j.str.2017.11.011

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