Distinct SoxB1 networks are required for naïve and primed pluripotency

Deletion of Sox2 from mouse embryonic stem cells (ESCs) causes trophectodermal differentiation. While this can be prevented by enforced expression of the related SOXB1 proteins, SOX1 or SOX3, the roles of SOXB1 proteins in epiblast stem cell (EpiSC) pluripotency are unknown. Here, we show that Sox2...

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Detalles Bibliográficos
Autores principales: Corsinotti, Andrea, Wong, Frederick CK, Tatar, Tülin, Szczerbinska, Iwona, Halbritter, Florian, Colby, Douglas, Gogolok, Sabine, Pantier, Raphaël, Liggat, Kirsten, Mirfazeli, Elham S, Hall-Ponsele, Elisa, Mullin, Nicholas P, Wilson, Valerie, Chambers, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Stem Cells and Regenerative Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758114/
https://www.ncbi.nlm.nih.gov/pubmed/29256862
http://dx.doi.org/10.7554/eLife.27746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758114/
https://www.ncbi.nlm.nih.gov/pubmed/29256862
http://dx.doi.org/10.7554/eLife.27746

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