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Functional divergence of paralogous transcription factors supported the evolution of biomineralization in echinoderms

Alx1 is a pivotal transcription factor in a gene regulatory network that controls skeletogenesis throughout the echinoderm phylum. We performed a structure-function analysis of sea urchin Alx1 using a rescue assay and identified a novel, conserved motif (Domain 2) essential for skeletogenic function...

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Detalles Bibliográficos
Autores principales:	Khor, Jian Ming, Ettensohn, Charles A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2017
Materias:	Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758115/ https://www.ncbi.nlm.nih.gov/pubmed/29154754 http://dx.doi.org/10.7554/eLife.32728

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