Sphingolipid Metabolism Is Dysregulated at Transcriptomic and Metabolic Levels in the Spinal Cord of an Animal Model of Amyotrophic Lateral Sclerosis

Lipid metabolism is drastically dysregulated in amyotrophic lateral sclerosis and impacts prognosis of patients. Animal models recapitulate alterations in the energy metabolism, including hypermetabolism and severe loss of adipose tissue. To gain insight into the molecular mechanisms underlying dise...

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Detalles Bibliográficos
Autores principales: Henriques, Alexandre, Croixmarie, Vincent, Bouscary, Alexandra, Mosbach, Althéa, Keime, Céline, Boursier-Neyret, Claire, Walter, Bernard, Spedding, Michael, Loeffler, Jean-Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758557/
https://www.ncbi.nlm.nih.gov/pubmed/29354030
http://dx.doi.org/10.3389/fnmol.2017.00433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758557/
https://www.ncbi.nlm.nih.gov/pubmed/29354030
http://dx.doi.org/10.3389/fnmol.2017.00433

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