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Rimonabant Kills Colon Cancer Stem Cells without Inducing Toxicity in Normal Colon Organoids

Colorectal cancer (CRC), like other tumor types, is a highly heterogeneous disease. Within the tumor bulk, intra-tumoral heterogeneity is also ascribable to Cancer Stem Cells (CSCs) subpopulation, characterized by high chemoresistance and the unique ability to retain tumorigenic potential, thus asso...

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Detalles Bibliográficos
Autores principales:	Fiore, Donatella, Ramesh, Prashanthi, Proto, Maria C., Piscopo, Chiara, Franceschelli, Silvia, Anzelmo, Serena, Medema, Jan P., Bifulco, Maurizio, Gazzerro, Patrizia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758598/ https://www.ncbi.nlm.nih.gov/pubmed/29354056 http://dx.doi.org/10.3389/fphar.2017.00949

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