Determinants of E2-ubiquitin conjugate recognition by RBR E3 ligases

RING-between-RING (RBR) ubiquitin ligases work with multiple E2 enzymes and function through an E3-ubiquitin thioester intermediate. The RBR module comprises three domains, RING1, IBR and RING2 that collaborate to transfer ubiquitin from the E2~Ub conjugate, recognised by RING1, onto a catalytic cys...

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Detalles Bibliográficos
Autores principales: Martino, Luigi, Brown, Nicholas R., Masino, Laura, Esposito, Diego, Rittinger, Katrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758712/
https://www.ncbi.nlm.nih.gov/pubmed/29311602
http://dx.doi.org/10.1038/s41598-017-18513-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758712/
https://www.ncbi.nlm.nih.gov/pubmed/29311602
http://dx.doi.org/10.1038/s41598-017-18513-5

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