Blockade of soluble epoxide hydrolase attenuates post-ischemic neuronal hyperexcitation and confers resilience against stroke with TrkB activation

Inhibition and deletion of soluble epoxide hydrolase (sEH) has been suggested to ameliorate infarction in experimental ischemic stroke possibly via vasoactive epoxyeicosatrienoic acids. However, it is unknown whether the neuroprotective mechanisms involve alteration of post-ischemic neuronal transmi...

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Detalles Bibliográficos
Autores principales: Chang, Li-Hsin, Lin, Hui-Ching, Huang, Shiang-Suo, Chen, I-Chih, Chu, Kai-Wen, Chih, Chun-Lien, Liang, Yao-Wen, Lee, Yi-Chung, Chen, You-Yin, Lee, Yi-Hsuan, Lee, I-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758800/
https://www.ncbi.nlm.nih.gov/pubmed/29311641
http://dx.doi.org/10.1038/s41598-017-18558-6

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