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Heme promotes transcriptional and demethylase activities of Gis1, a member of the histone demethylase JMJD2/KDM4 family

The yeast Gis1 protein is a transcriptional regulator belonging to the JMJD2/KDM4 subfamily of demethylases that contain a JmjC domain, which are highly conserved from yeast to humans. They have important functions in histone methylation, cellular signaling and tumorigenesis. Besides serving as a co...

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Detalles Bibliográficos
Autores principales:	Lal, Sneha, Comer, Jonathan M, Konduri, Purna C, Shah, Ajit, Wang, Tianyuan, Lewis, Anthony, Shoffner, Grant, Guo, Feng, Zhang, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758875/ https://www.ncbi.nlm.nih.gov/pubmed/29126261 http://dx.doi.org/10.1093/nar/gkx1051

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