Regulation of transcriptional silencing and chromodomain protein localization at centromeric heterochromatin by histone H3 tyrosine 41 phosphorylation in fission yeast

Heterochromatin silencing is critical for genomic integrity and cell survival. It is orchestrated by chromodomain (CD)-containing proteins that bind to methylated histone H3 lysine 9 (H3K9me), a hallmark of heterochromatin. Here, we show that phosphorylation of tyrosine 41 (H3Y41p)—a novel histone H...

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Detalles Bibliográficos
Autores principales: Ren, Bingbing, Tan, Hwei Ling, Nguyen, Thi Thuy Trang, Sayed, Ahmed Mahmoud Mohammed, Li, Ying, Mok, Yu-Keung, Yang, Henry, Chen, Ee Sin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758876/
https://www.ncbi.nlm.nih.gov/pubmed/29136238
http://dx.doi.org/10.1093/nar/gkx1010

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