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The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia

Cells adapt to environmental changes, including fluctuations in oxygen levels, through the induction of specific gene expression programs. To identify genes regulated by hypoxia at the transcriptional level, we pulse-labeled HUVEC cells with 4-thiouridine and sequenced nascent transcripts. Then, we...

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Detalles Bibliográficos
Autores principales:	Tiana, Maria, Acosta-Iborra, Barbara, Puente-Santamaría, Laura, Hernansanz-Agustin, Pablo, Worsley-Hunt, Rebecca, Masson, Norma, García-Rio, Francisco, Mole, David, Ratcliffe, Peter, Wasserman, Wyeth W, Jimenez, Benilde, del Peso, Luis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758878/ https://www.ncbi.nlm.nih.gov/pubmed/29059365 http://dx.doi.org/10.1093/nar/gkx951

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