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Conformational dynamics of the Hop1 HORMA domain reveal a common mechanism with the spindle checkpoint protein Mad2

The HORMA domain is a highly conserved protein–protein interaction module found in eukaryotic signaling proteins including the spindle assembly checkpoint protein Mad2 and the meiotic HORMAD proteins. HORMA domain proteins interact with short ‘closure motifs’ in partner proteins by wrapping their C-...

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Detalles Bibliográficos
Autores principales:	West, Alan M V, Komives, Elizabeth A, Corbett, Kevin D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758881/ https://www.ncbi.nlm.nih.gov/pubmed/29186573 http://dx.doi.org/10.1093/nar/gkx1196

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