Human cancer tissues exhibit reduced A-to-I editing of miRNAs coupled with elevated editing of their targets

A-to-I RNA editing is an important post-transcriptional modification, known to be altered in tumors. It targets dozens of sites within miRNAs, some of which impact miRNA biogenesis and function, as well as many miRNA recognition sites. However, the full extent of the effect of editing on regulation...

Descripción completa

Detalles Bibliográficos
Autores principales: Pinto, Yishay, Buchumenski, Ilana, Levanon, Erez Y, Eisenberg, Eli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758889/
https://www.ncbi.nlm.nih.gov/pubmed/29165639
http://dx.doi.org/10.1093/nar/gkx1176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758889/
https://www.ncbi.nlm.nih.gov/pubmed/29165639
http://dx.doi.org/10.1093/nar/gkx1176

Ejemplares similares