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Dynamic motif occupancy (DynaMO) analysis identifies transcription factors and their binding sites driving dynamic biological processes

Biological processes are usually associated with genome-wide remodeling of transcription driven by transcription factors (TFs). Identifying key TFs and their spatiotemporal binding patterns are indispensable to understanding how dynamic processes are programmed. However, most methods are designed to...

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Detalles Bibliográficos
Autores principales: Kuang, Zheng, Ji, Zhicheng, Boeke, Jef D, Ji, Hongkai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758894/
https://www.ncbi.nlm.nih.gov/pubmed/29325176
http://dx.doi.org/10.1093/nar/gkx905