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Integrating sequence and gene expression information predicts genome-wide DNA-binding proteins and suggests a cooperative mechanism
DNA-binding proteins (DBPs) perform diverse biological functions ranging from transcription to pathogen sensing. Machine learning methods can not only identify DBPs de novo but also provide insights into their DNA-recognition dynamics. However, it remains unclear whether available methods that can a...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5758906/ https://www.ncbi.nlm.nih.gov/pubmed/29186632 http://dx.doi.org/10.1093/nar/gkx1166 |