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Commentary: considerations for using the ‘Trials within Cohorts’ design in a clinical trial of an investigational medicinal product

BACKGROUND: The ‘trials within cohorts’ (TwiC) design is a pragmatic approach to randomised trials in which trial participants are randomly selected from an existing cohort. The design has multiple potential benefits, including the option of conducting multiple trials within the same cohort. MAIN TE...

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Detalles Bibliográficos
Autores principales: Bibby, Anna C., Torgerson, David J., Leach, Samantha, Lewis-White, Helen, Maskell, Nick A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5759253/
https://www.ncbi.nlm.nih.gov/pubmed/29310706
http://dx.doi.org/10.1186/s13063-017-2432-3