Dopamine Transporter Neuroimaging as an Enrichment Biomarker in Early Parkinson's Disease Clinical Trials: A Disease Progression Modeling Analysis

Given the recognition that disease‐modifying therapies should focus on earlier Parkinson's disease stages, trial enrollment based purely on clinical criteria poses significant challenges. The goal herein was to determine the utility of dopamine transporter neuroimaging as an enrichment biomarke...

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Detalles Bibliográficos
Autores principales: Conrado, Daniela J., Nicholas, Timothy, Tsai, Kuenhi, Macha, Sreeraj, Sinha, Vikram, Stone, Julie, Corrigan, Brian, Bani, Massimo, Muglia, Pierandrea, Watson, Ian A., Kern, Volker D., Sheveleva, Elena, Marek, Kenneth, Stephenson, Diane T., Romero, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5759747/
https://www.ncbi.nlm.nih.gov/pubmed/28749580
http://dx.doi.org/10.1111/cts.12492

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