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Consensus Guideline for Use of Glucarpidase in Patients with High‐Dose Methotrexate Induced Acute Kidney Injury and Delayed Methotrexate Clearance

Acute kidney injury due to high‐dose methotrexate (HDMTX) is a serious, life‐threatening toxicity that can occur in pediatric and adult patients. Glucarpidase is a treatment approved by the Food and Drug Administration for high methotrexate concentrations in the context of kidney dysfunction, but th...

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Detalles Bibliográficos
Autores principales:	Ramsey, Laura B., Balis, Frank M., O'Brien, Maureen M., Schmiegelow, Kjeld, Pauley, Jennifer L., Bleyer, Archie, Widemann, Brigitte C., Askenazi, David, Bergeron, Sharon, Shirali, Anushree, Schwartz, Stefan, Vinks, Alexander A., Heldrup, Jesper
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AlphaMed Press 2017
Materias:	New Drug Development and Clinical Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5759822/ https://www.ncbi.nlm.nih.gov/pubmed/29079637 http://dx.doi.org/10.1634/theoncologist.2017-0243

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