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Dysregulation of valvular interstitial cell let-7c, miR-17, miR-20a, and miR-30d in naturally occurring canine myxomatous mitral valve disease

Canine myxomatous mitral valve disease (MMVD) resembles the early stages of myxomatous pathology seen in human non-syndromic mitral valve prolapse, a common valvular heart disease in the adult human population. Canine MMVD is seen in older subjects, suggesting age-related epigenetic dysregulation le...

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Detalles Bibliográficos
Autores principales: Yang, Vicky K., Tai, Albert K., Huh, Terry P., Meola, Dawn M., Juhr, Christine M., Robinson, Nicholas A., Hoffman, Andrew M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760013/
https://www.ncbi.nlm.nih.gov/pubmed/29315310
http://dx.doi.org/10.1371/journal.pone.0188617

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