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The C3aR promotes macrophage infiltration and regulates ANCA production but does not affect glomerular injury in experimental anti-myeloperoxidase glomerulonephritis
The anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitides are autoimmune diseases associated with significant morbidity and mortality. They often affect the kidney causing rapidly progressive glomerulonephritis. While signalling by complement anaphylatoxin C5a though the C5a receptor i...
Autores principales: | Dick, Jonathan, Gan, Poh-Yi, Kitching, A. Richard, Holdsworth, Stephen R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760037/ https://www.ncbi.nlm.nih.gov/pubmed/29315316 http://dx.doi.org/10.1371/journal.pone.0190655 |
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