Histone demethylase LSD1 restricts influenza A virus infection by erasing IFITM3-K88 monomethylation

The histone demethylase LSD1 has been known as a key transcriptional coactivator for DNA viruses such as herpes virus. Inhibition of LSD1 was found to block viral genome transcription and lytic replication of DNA viruses. However, RNA virus genomes do not rely on chromatin structure and histone asso...

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Detalles Bibliográficos
Autores principales: Shan, Jiaoyu, Zhao, Binbin, Shan, Zhao, Nie, Jia, Deng, Rong, Xiong, Rui, Tsun, Andy, Pan, Weiqi, Zhao, Hanzhi, Chen, Ling, Jin, Ying, Qian, Zhikang, Lui, Kawing, Liang, Rui, Li, Dan, Sun, Bing, Lavillette, Dimitri, Xu, Ke, Li, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760097/
https://www.ncbi.nlm.nih.gov/pubmed/29281729
http://dx.doi.org/10.1371/journal.ppat.1006773

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