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RNA elongation by respiratory syncytial virus polymerase is calibrated by conserved region V
The large polymerase subunit (L) of non-segmented negative strand RNA viruses transcribes viral mRNAs and replicates the viral genome. Studies with VSV have shown that conserved region V (CRV) of the L protein is part of the capping domain. However, CRV folds over and protrudes into the polymerizati...
Autores principales: | Braun, Molly R., Deflubé, Laure R., Noton, Sarah L., Mawhorter, Michael E., Tremaglio, Chadene Z., Fearns, Rachel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760109/ https://www.ncbi.nlm.nih.gov/pubmed/29281742 http://dx.doi.org/10.1371/journal.ppat.1006803 |
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