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Aggressive neuroendocrine tumor of the ovary with multiple metastases treated with everolimus: A case report

• Neuroendocrine tumors (NETs) frequently occur in the lungs or the gastrointestinal tract; they are uncommon in the ovary. • The mammalian target of rapamycin (mTOR) pathway has been reported as a treatment for advanced NETs. • We describe a patient with an aggressive primary ovarian NET, successfu...

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Detalles Bibliográficos
Autores principales: Kaiho-Sakuma, Michiko, Toyoshima, Masafumi, Watanabe, Mika, Toki, Asami, Kameda, Satomi, Minato, Takamichi, Niikura, Hitoshi, Yaegashi, Nobuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760241/
https://www.ncbi.nlm.nih.gov/pubmed/29326972
http://dx.doi.org/10.1016/j.gore.2018.01.002
Descripción
Sumario:• Neuroendocrine tumors (NETs) frequently occur in the lungs or the gastrointestinal tract; they are uncommon in the ovary. • The mammalian target of rapamycin (mTOR) pathway has been reported as a treatment for advanced NETs. • We describe a patient with an aggressive primary ovarian NET, successfully treated with everolimus (an mTOR inhibitor).