A single-cysteine mutant and chimeras of essential Leishmania Erv can complement the loss of Erv1 but not of Mia40 in yeast

Mia40/CHCHD4 and Erv1/ALR are essential for oxidative protein folding in the mitochondrial intermembrane space of yeast and mammals. In contrast, many protists, including important apicomplexan and kinetoplastid parasites, lack Mia40. Furthermore, the Erv homolog of the model parasite Leishmania tar...

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Detalles Bibliográficos
Autores principales: Specht, Sandra, Liedgens, Linda, Duarte, Margarida, Stiegler, Alexandra, Wirth, Ulrike, Eberhardt, Maike, Tomás, Ana, Hell, Kai, Deponte, Marcel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760468/
https://www.ncbi.nlm.nih.gov/pubmed/29310075
http://dx.doi.org/10.1016/j.redox.2017.12.010

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