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Regulation of RIG-I Activation by K63-Linked Polyubiquitination

RIG-I is a pattern recognition receptor and recognizes cytoplasmic viral double-stranded RNA (dsRNA). Influenza A virus, hepatitis C virus, and several other pathogenic viruses are mainly recognized by RIG-I, resulting in the activation of the innate immune responses. The protein comprises N-termina...

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Detalles Bibliográficos
Autores principales:	Okamoto, Masaaki, Kouwaki, Takahisa, Fukushima, Yoshimi, Oshiumi, Hiroyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760545/ https://www.ncbi.nlm.nih.gov/pubmed/29354136 http://dx.doi.org/10.3389/fimmu.2017.01942

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