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Illness Perceptions are Associated with Quality of Life in Patients with Fibrous Dysplasia

Fibrous dysplasia (FD) is a rare bone disorder in which normal bone is replaced by fibrous tissue resulting in pain, deformities, pathological fractures or asymptomatic disease. Illness perceptions are patients’ cognitions and emotions about their illness and its treatment, which may impact on Quali...

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Autores principales: Majoor, B. C. J., Andela, C. D., Quispel, C. R., Rotman, M., Dijkstra, P. D. S., Hamdy, N. A. T., Kaptein, A. A., Appelman-Dijkstra, N. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760610/
https://www.ncbi.nlm.nih.gov/pubmed/29022055
http://dx.doi.org/10.1007/s00223-017-0329-5
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author Majoor, B. C. J.
Andela, C. D.
Quispel, C. R.
Rotman, M.
Dijkstra, P. D. S.
Hamdy, N. A. T.
Kaptein, A. A.
Appelman-Dijkstra, N. M.
author_facet Majoor, B. C. J.
Andela, C. D.
Quispel, C. R.
Rotman, M.
Dijkstra, P. D. S.
Hamdy, N. A. T.
Kaptein, A. A.
Appelman-Dijkstra, N. M.
author_sort Majoor, B. C. J.
collection PubMed
description Fibrous dysplasia (FD) is a rare bone disorder in which normal bone is replaced by fibrous tissue resulting in pain, deformities, pathological fractures or asymptomatic disease. Illness perceptions are patients’ cognitions and emotions about their illness and its treatment, which may impact on Quality of Life (QoL). Here, we explore illness perceptions in patients with FD compared to other disorders, identify factors associated with illness perceptions and evaluate their relationship with QoL. Ninety-seven out of 138 eligible patients from the LUMC FD cohort completed the Illness Perception Questionnaire-Revised (IPQ-R) and the Short Form-36 (SF-36). Age, Gender, Skeletal Burden Score (SBS), FGF-23 levels, type of FD and SF-36 scores were analysed for an association with illness perceptions. We observed significant (p < 0.01) differences in patients’ illness perceptions between FD subtypes in the domains: identity, timeline acute/chronic and consequences. Patients with craniofacial FD reported to perceive more consequences (p = 0.022). High SBS was associated with perceiving more negative consequences and attributing the cause of FD to psychological factors (p < 0.01), and high FGF-23 levels with attributing more symptoms to the disease and perceiving more consequences (p < 0.01). The IPQ-R domain identity, timeline acute/chronic, timeline cyclical, consequences, emotional representations and treatment control were significantly associated with impairments in QoL. Illness perceptions in patients with FD relate to QoL, differ from those in patients with other disorders, and are associated with disease severity. Identifying and addressing maladaptive illness perceptions may improve quality of life in patients with FD. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00223-017-0329-5) contains supplementary material, which is available to authorized users.
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spelling pubmed-57606102018-01-22 Illness Perceptions are Associated with Quality of Life in Patients with Fibrous Dysplasia Majoor, B. C. J. Andela, C. D. Quispel, C. R. Rotman, M. Dijkstra, P. D. S. Hamdy, N. A. T. Kaptein, A. A. Appelman-Dijkstra, N. M. Calcif Tissue Int Original Research Fibrous dysplasia (FD) is a rare bone disorder in which normal bone is replaced by fibrous tissue resulting in pain, deformities, pathological fractures or asymptomatic disease. Illness perceptions are patients’ cognitions and emotions about their illness and its treatment, which may impact on Quality of Life (QoL). Here, we explore illness perceptions in patients with FD compared to other disorders, identify factors associated with illness perceptions and evaluate their relationship with QoL. Ninety-seven out of 138 eligible patients from the LUMC FD cohort completed the Illness Perception Questionnaire-Revised (IPQ-R) and the Short Form-36 (SF-36). Age, Gender, Skeletal Burden Score (SBS), FGF-23 levels, type of FD and SF-36 scores were analysed for an association with illness perceptions. We observed significant (p < 0.01) differences in patients’ illness perceptions between FD subtypes in the domains: identity, timeline acute/chronic and consequences. Patients with craniofacial FD reported to perceive more consequences (p = 0.022). High SBS was associated with perceiving more negative consequences and attributing the cause of FD to psychological factors (p < 0.01), and high FGF-23 levels with attributing more symptoms to the disease and perceiving more consequences (p < 0.01). The IPQ-R domain identity, timeline acute/chronic, timeline cyclical, consequences, emotional representations and treatment control were significantly associated with impairments in QoL. Illness perceptions in patients with FD relate to QoL, differ from those in patients with other disorders, and are associated with disease severity. Identifying and addressing maladaptive illness perceptions may improve quality of life in patients with FD. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00223-017-0329-5) contains supplementary material, which is available to authorized users. Springer US 2017-10-11 2018 /pmc/articles/PMC5760610/ /pubmed/29022055 http://dx.doi.org/10.1007/s00223-017-0329-5 Text en © The Author(s) 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Research
Majoor, B. C. J.
Andela, C. D.
Quispel, C. R.
Rotman, M.
Dijkstra, P. D. S.
Hamdy, N. A. T.
Kaptein, A. A.
Appelman-Dijkstra, N. M.
Illness Perceptions are Associated with Quality of Life in Patients with Fibrous Dysplasia
title Illness Perceptions are Associated with Quality of Life in Patients with Fibrous Dysplasia
title_full Illness Perceptions are Associated with Quality of Life in Patients with Fibrous Dysplasia
title_fullStr Illness Perceptions are Associated with Quality of Life in Patients with Fibrous Dysplasia
title_full_unstemmed Illness Perceptions are Associated with Quality of Life in Patients with Fibrous Dysplasia
title_short Illness Perceptions are Associated with Quality of Life in Patients with Fibrous Dysplasia
title_sort illness perceptions are associated with quality of life in patients with fibrous dysplasia
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760610/
https://www.ncbi.nlm.nih.gov/pubmed/29022055
http://dx.doi.org/10.1007/s00223-017-0329-5
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