Exome-wide rare variant analyses of two bone mineral density phenotypes: the challenges of analyzing rare genetic variation

Performance of a recently developed test for association between multivariate phenotypes and sets of genetic variants (MURAT) is demonstrated using measures of bone mineral density (BMD). By combining individual-level whole genome sequenced data from the UK10K study, and imputed genome-wide genetic...

Descripción completa

Detalles Bibliográficos
Autores principales: Sun, Jianping, Oualkacha, Karim, Forgetta, Vincenzo, Zheng, Hou-Feng, Richards, J. Brent, Evans, Daniel S., Orwoll, Eric, Greenwood, Celia M. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760616/
https://www.ncbi.nlm.nih.gov/pubmed/29317680
http://dx.doi.org/10.1038/s41598-017-18385-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760616/
https://www.ncbi.nlm.nih.gov/pubmed/29317680
http://dx.doi.org/10.1038/s41598-017-18385-9

Ejemplares similares