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Non-coding RNAs predict recurrence-free survival of patients with hypoxic tumours

Hypoxia promotes tumour aggressiveness and reduces patient survival. A spectrum of poor outcome among patients with hypoxic tumours suggests that additional factors modulate how tumours respond to hypoxia. PIWI-interacting RNAs (piRNAs) are small non-coding RNAs with a pivotal role in genomic stabil...

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Detalles Bibliográficos
Autores principales: Martinez, Victor D., Firmino, Natalie S., Marshall, Erin A., Ng, Kevin W., Wadsworth, Brennan J., Anderson, Christine, Lam, Wan L., Bennewith, Kevin L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760628/
https://www.ncbi.nlm.nih.gov/pubmed/29317756
http://dx.doi.org/10.1038/s41598-017-18462-z