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Experimental noise cutoff boosts inferability of transcriptional networks in large-scale gene-deletion studies
Generating a comprehensive map of molecular interactions in living cells is difficult and great efforts are undertaken to infer molecular interactions from large-scale perturbation experiments. Here, we develop the analytical and numerical tools to quantify the fundamental limits for inferring trans...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760630/ https://www.ncbi.nlm.nih.gov/pubmed/29317620 http://dx.doi.org/10.1038/s41467-017-02489-x |