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Protein tyrosine kinase, PtkA, is required for Mycobacterium tuberculosis growth in macrophages
Protein phosphorylation plays a key role in Mycobacterium tuberculosis (Mtb) physiology and pathogenesis. We have previously shown that a secreted protein tyrosine phosphatase, PtpA, is essential for Mtb inhibition of host macrophage acidification and maturation, and is a substrate of the protein ty...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760654/ https://www.ncbi.nlm.nih.gov/pubmed/29317718 http://dx.doi.org/10.1038/s41598-017-18547-9 |