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Protein tyrosine kinase, PtkA, is required for Mycobacterium tuberculosis growth in macrophages

Protein phosphorylation plays a key role in Mycobacterium tuberculosis (Mtb) physiology and pathogenesis. We have previously shown that a secreted protein tyrosine phosphatase, PtpA, is essential for Mtb inhibition of host macrophage acidification and maturation, and is a substrate of the protein ty...

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Detalles Bibliográficos
Autores principales:	Wong, Dennis, Li, Wu, Chao, Joseph D., Zhou, Peifu, Narula, Gagandeep, Tsui, Clement, Ko, Mary, Xie, Jianping, Martinez-Frailes, Carlos, Av-Gay, Yossef
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760654/ https://www.ncbi.nlm.nih.gov/pubmed/29317718 http://dx.doi.org/10.1038/s41598-017-18547-9

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