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TDRD5 binds piRNA precursors and selectively enhances pachytene piRNA processing in mice

Pachytene piRNAs are the most abundant piRNAs in mammalian adult testes. They are generated from long precursor transcripts by the primary piRNA biogenesis pathway but the factors involved in pachytene piRNA precursors processing are poorly understood. Here we show that the Tudor domain-containing 5...

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Detalles Bibliográficos
Autores principales: Ding, Deqiang, Liu, Jiali, Midic, Uros, Wu, Yingjie, Dong, Kunzhe, Melnick, Ashley, Latham, Keith E., Chen, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760656/
https://www.ncbi.nlm.nih.gov/pubmed/29317670
http://dx.doi.org/10.1038/s41467-017-02622-w