Brain Atrophy and Hypomyelination Associated with Iatrogenic Cushing Syndrome in an Infant

Prolonged use of topical corticosteroids, particularly in infants, albeit rare, may lead to Cushing syndrome. Central nervous system abnormalities including brain atrophy and delayed myelination on cranial magnetic resonance imaging has been reported in patients with corticosteroid treatment. We her...

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Detalles Bibliográficos
Autores principales: DOGAN, Sumeyra, S DOGAN, Mehmet, TUTUNCULER, Filiz, YAPICIUGURLAR, Ozge, GENCHELLAC, Hakan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shahid Beheshti University of Medical Sciences 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760680/
https://www.ncbi.nlm.nih.gov/pubmed/29379569
Descripción
Sumario:Prolonged use of topical corticosteroids, particularly in infants, albeit rare, may lead to Cushing syndrome. Central nervous system abnormalities including brain atrophy and delayed myelination on cranial magnetic resonance imaging has been reported in patients with corticosteroid treatment. We herein report a 5-month-old female infant referred to Department of Pediatric Endocrinology, Edirne, Turkey with brain atrophy and myelination delay that might be due to iatrogenic Cushing syndrome caused by topical corticosteroid use.

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