Brain Atrophy and Hypomyelination Associated with Iatrogenic Cushing Syndrome in an Infant

Prolonged use of topical corticosteroids, particularly in infants, albeit rare, may lead to Cushing syndrome. Central nervous system abnormalities including brain atrophy and delayed myelination on cranial magnetic resonance imaging has been reported in patients with corticosteroid treatment. We her...

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Autores principales: DOGAN, Sumeyra, S DOGAN, Mehmet, TUTUNCULER, Filiz, YAPICIUGURLAR, Ozge, GENCHELLAC, Hakan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shahid Beheshti University of Medical Sciences 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760680/
https://www.ncbi.nlm.nih.gov/pubmed/29379569
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author DOGAN, Sumeyra
S DOGAN, Mehmet
TUTUNCULER, Filiz
YAPICIUGURLAR, Ozge
GENCHELLAC, Hakan
author_facet DOGAN, Sumeyra
S DOGAN, Mehmet
TUTUNCULER, Filiz
YAPICIUGURLAR, Ozge
GENCHELLAC, Hakan
author_sort DOGAN, Sumeyra
collection PubMed
description Prolonged use of topical corticosteroids, particularly in infants, albeit rare, may lead to Cushing syndrome. Central nervous system abnormalities including brain atrophy and delayed myelination on cranial magnetic resonance imaging has been reported in patients with corticosteroid treatment. We herein report a 5-month-old female infant referred to Department of Pediatric Endocrinology, Edirne, Turkey with brain atrophy and myelination delay that might be due to iatrogenic Cushing syndrome caused by topical corticosteroid use.
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spelling pubmed-57606802018-04-01 Brain Atrophy and Hypomyelination Associated with Iatrogenic Cushing Syndrome in an Infant DOGAN, Sumeyra S DOGAN, Mehmet TUTUNCULER, Filiz YAPICIUGURLAR, Ozge GENCHELLAC, Hakan Iran J Child Neurol Case Report Prolonged use of topical corticosteroids, particularly in infants, albeit rare, may lead to Cushing syndrome. Central nervous system abnormalities including brain atrophy and delayed myelination on cranial magnetic resonance imaging has been reported in patients with corticosteroid treatment. We herein report a 5-month-old female infant referred to Department of Pediatric Endocrinology, Edirne, Turkey with brain atrophy and myelination delay that might be due to iatrogenic Cushing syndrome caused by topical corticosteroid use. Shahid Beheshti University of Medical Sciences 2018 /pmc/articles/PMC5760680/ /pubmed/29379569 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
DOGAN, Sumeyra
S DOGAN, Mehmet
TUTUNCULER, Filiz
YAPICIUGURLAR, Ozge
GENCHELLAC, Hakan
Brain Atrophy and Hypomyelination Associated with Iatrogenic Cushing Syndrome in an Infant
title Brain Atrophy and Hypomyelination Associated with Iatrogenic Cushing Syndrome in an Infant
title_full Brain Atrophy and Hypomyelination Associated with Iatrogenic Cushing Syndrome in an Infant
title_fullStr Brain Atrophy and Hypomyelination Associated with Iatrogenic Cushing Syndrome in an Infant
title_full_unstemmed Brain Atrophy and Hypomyelination Associated with Iatrogenic Cushing Syndrome in an Infant
title_short Brain Atrophy and Hypomyelination Associated with Iatrogenic Cushing Syndrome in an Infant
title_sort brain atrophy and hypomyelination associated with iatrogenic cushing syndrome in an infant
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760680/
https://www.ncbi.nlm.nih.gov/pubmed/29379569
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