Cargando…
In vivo STED microscopy visualizes PSD95 sub-structures and morphological changes over several hours in the mouse visual cortex
The post-synaptic density (PSD) is an electron dense region consisting of ~1000 proteins, found at the postsynaptic membrane of excitatory synapses, which varies in size depending upon synaptic strength. PSD95 is an abundant scaffolding protein in the PSD and assembles a family of supercomplexes com...
Autores principales: | Wegner, Waja, Mott, Alexander C., Grant, Seth G. N., Steffens, Heinz, Willig, Katrin I. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760696/ https://www.ncbi.nlm.nih.gov/pubmed/29317733 http://dx.doi.org/10.1038/s41598-017-18640-z |
Ejemplares similares
-
In vivo mouse and live cell STED microscopy of neuronal actin plasticity using far-red emitting fluorescent proteins
por: Wegner, Waja, et al.
Publicado: (2017) -
Environmental enrichment enhances patterning and remodeling of synaptic nanoarchitecture as revealed by STED nanoscopy
por: Wegner, Waja, et al.
Publicado: (2022) -
Stable but not rigid: Chronic in vivo STED nanoscopy reveals extensive remodeling of spines, indicating multiple drivers of plasticity
por: Steffens, Heinz, et al.
Publicado: (2021) -
Spine dynamics of PSD-95-deficient neurons in the visual cortex link silent synapses to structural cortical plasticity
por: Yusifov, Rashad, et al.
Publicado: (2021) -
Durable fear memories require PSD-95
por: Fitzgerald, Paul J., et al.
Publicado: (2014)