Cargando…
Punctuated evolution of canonical genomic aberrations in uveal melanoma
Cancer is thought to arise through the accumulation of genomic aberrations evolving under Darwinian selection. However, it remains unclear when the aberrations associated with metastasis emerge during tumor evolution. Uveal melanoma (UM) is the most common primary eye cancer and frequently leads to...
Autores principales: | Field, Matthew G., Durante, Michael A., Anbunathan, Hima, Cai, Louis Z., Decatur, Christina L., Bowcock, Anne M., Kurtenbach, Stefan, Harbour, J. William |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5760704/ https://www.ncbi.nlm.nih.gov/pubmed/29317634 http://dx.doi.org/10.1038/s41467-017-02428-w |
Ejemplares similares
-
Epigenetic reprogramming and aberrant expression of PRAME are associated with increased metastatic risk in Class 1 and Class 2 uveal melanomas
por: Field, Matthew G., et al.
Publicado: (2016) -
Genomic evolution of uveal melanoma arising in ocular melanocytosis
por: Durante, Michael A., et al.
Publicado: (2019) -
PRAME induces genomic instability in uveal melanoma
por: Kurtenbach, Stefan, et al.
Publicado: (2023) -
Recurrent mutations at codon 625 of the splicing factor SF3B1 in uveal melanoma
por: Harbour, J. William, et al.
Publicado: (2013) -
Single-cell analysis reveals new evolutionary complexity in uveal melanoma
por: Durante, Michael A., et al.
Publicado: (2020)